皮肤病学和皮肤病杂志

Rare Case Report of Angiolymphoid Hyperplasia with Eosinophilia

Abstract

RK Belkharoeva, AR Hubail, NP Tepljuk, OY Olisova, VB Pinegin and VA Koroleva

Aims and objective: The aim of this study was to assess the clinical and demographic features of a rare cutaneous condition, angiolymphoid hyperplasia with eosinophilia (ALHE), and compare them with those previously reported. ALHE is a benign vascular proliferation of unknown etiology and its treatment is unclear. Methods: A 29 year old woman visited the Hospital of Skin and Venereal diseases for pruritic lesion in the ear. She presented with a reddish papulonodular rash. Laboratory tests showed no abnormalities. She was diagnosed with ALHE based on clinical, histological, and immunological features. Treatment with injectable prolonged systemic glucocorticoid and topical prednisolone was initiated. The rash and pruritic sensation improved within one week in the hospital, and the reddish infiltration and nodules had dramatically decreased at the 6 month follow-up. Continuous topical application resulted in no recurrence at the 6 month follow-up. Results and conclusion: Management of ALHE is still poorly standardized and poorly understood due to uncertainties concerning its pathophysiology and development and the small number of available studies. Establishing the final clinical diagnosis is difficult owing to the absence of subjective sensations. ALHE can persist for years but serious complications like cancer transformation do not occur.